A microRNA prevents cervical embryonic implantation
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چکیده
منابع مشابه
Interleukin-1 receptor antagonist prevents embryonic implantation by a direct effect on the endometrial epithelium.
OBJECTIVE To investigate the embryonic and/or endometrial molecular mechanisms underlying the antiimplantation effect of interleukin-1 receptor antagonist (IL-1ra). DESIGN Controlled experiment. SETTING Animal facilities at Stanford University and laboratories of the Instituto Valenciano de Infertilidad and the University of Sydney. ANIMAL(S) Twelve-week-old B6C3F-1 female mice. INTERVE...
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The preimplantation embryo produces several factors during its development to signal its presence to the maternal organism. This paper will focus on the role of two distinctive cytokine and growth factor systems (interleukin-1 (IL-1) system and the vascular endothelial growth factor (VEGF) system) during early embryonic development and implantation. IL-1 receptor is expressed in the endometrium...
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Embryo implantation consists of a series of events promoting the invasion of the endometrium and then the uterine arterial system by the extra-embryonic trophoblast. In order for this semi-heterologous implantation to succeed, the endometrium has to first undergo a number of structural and biochemical changes (decidualization). The decidua's various constituents subsequently play a role in the ...
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Human endometrium has been extensively investigated in the search for markers capable of predicting its receptive status. The completion of the Human Genome Project has triggered a rapid development of new fields in molecular biology, the "transcriptomics" being a major turning point in the knowledge acquisition of endometrial receptivity. Based on this, a customized Endometrial Receptivity Arr...
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PROBLEM Implantation failure is common in women with advanced maternal age, partly because of the increased number of aneuploid embryos. These women constitute the majority of patients for IVF treatment. As multiple pregnancies is a major hazard of preterm delivery, the aim is to select a competent embryo for single transfer. This study reviews currently used methods for selecting the competent...
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ژورنال
عنوان ژورنال: Nature Reviews Endocrinology
سال: 2014
ISSN: 1759-5029,1759-5037
DOI: 10.1038/nrendo.2014.93